Many studies have been carried out on the toxicity of pollutants to aquatic animals , most of them are focused on the information of lethal concentrations , few have concerned the effects of sublethal concentration on the metabolism conditions 在污染物對于水生生物的毒害作用方面已經(jīng)進行了大量的研究,但是大多為毒物致死濃度方面的報道,而關(guān)于在亞致死濃度時它們對于機體的生理影響卻很少報道。
Nci - h1155 , a human non - small - cell lung cancer line , was employed in a paclitaxel - dependent synthetic lethal screen designed to identify gene targets that specifically reduce cell iability in the presence of otherwise sublethal concentrations of paclitaxel Nci - h1155作為一種人類非小細胞肺癌的種株,可運用其在依賴紫杉醇殺傷性藥物合成過程中設(shè)計鑒別出靶基因,從而特異性減少未達到殺傷性致死量的紫杉醇藥物作用后腫瘤細胞仍存活的數(shù)量。